Zynacort

Oral Prednisolone Solution (as Sodium Phosphate)
15 mg / 5 mL

Product Features: Supplied with an oral dosing adaptor and a 5 mL syringe for accurate dosing; berry-flavored to improve pediatric adherence.

Indications :

Allergic and hypersensitivity disorders
Autoimmune and inflammatory diseases
Rheumatic and connective tissue disorders
Dermatologic diseases
Respiratory diseases
Gastrointestinal diseases
Renal diseases
Hematologic disorders
Endocrine disorders
Ophthalmic diseases
Neurological disorders
Selected neoplastic conditions

Dosage and Administration:

Prednisolone is used as part of standard or adjunctive therapy in accordance with clinical guidelines and physician prescription.

Dosage and duration of treatment should be individualized based on the patient’s clinical condition, disease severity, and physician’s judgment.

Common Adverse Effects:

• Short-term: Insomnia, irritability, increased appetite and weight gain, hyperglycemia
• Long-term: Growth suppression, osteoporosis, hypertension,
recurrent infections, glaucoma
• Gastrointestinal: Nausea, abdominal pain, gastric ulcer

Drug Interactions:

• Oral anticoagulants (may increase bleeding risk)
• Diuretics (risk of electrolyte imbalance, especially hypokalemia)
• Antidiabetic agents (may reduce efficacy)
• Anticonvulsants (may alter prednisolone metabolism and reduce
therapeutic efficacy)

References:
1. Swaiman’s Pediatric Neurology: Principles and Practice. 7th ed. Elsevier Health Sciences; 2025.
2. Fenichel’s Clinical Pediatric Neurology. 9th ed. Elsevier; 2024.