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Strocol Tablet

RELIVING MEMORIES

Citicoline

Leaflet
Catalogue

Citicoline, 500 mg tablets
Other ingredients: Polyviny|pyrrolidone, Magnesium stearate, Colloidal silicon dioxide, Croscarmellose sodium.
Indication: Poststrok recovery, cognitive impairment, Alzheimer’s disease, Parkinson’s disease, memory and behavioral dysfunction in elderly, attention deficit hyperactivity disorder(ADHD), glaucoma, amblyopia.
Dosing: 1 tablet per day
Contraindication: Allergic to any ingredient in Strocol.
Side effects: no serious adverse effects have been reported to date. But side effects may include dizziness and gastrointestinal problems like nausea.
Pregnancy & Lactation: Since there is no evidence related to taking Strocol in pregnancy and breast feeding, consult your doctor before taking this product.
Precaution: In case of Parkinson’s disease please consult your doctor for dose adjustment before taking it.
Strocol is a product of Ashbal Chemi

What is STROCOL?
Strocol contains citicoline (citidine-5'-diphosphocholine) which is an endogenous nucleotide naturally found in the body, where it is an essential intermediate in the synthesis of the phosphatidylcholine, the major phospholipid of the cell membranes.
Literature Review
A trial lasting for 6 months in 172 patients with first-ever ischemic stroke showed that citicoline prevented cognitive decline after stroke. Significant reduction in cognitive impairment was seen in the domains of attention, temporal orientation, and executive functions. A randomized, double-blind, placebo-controlled, parallel group designed study with 95 elderly subjects showed that citicoline therapy improved verbal memory functioning and can be effective in treating age-related cognitive decline. A randomized, double-blind, placebo-controlled, three-arm designed study with 75 adolescents showed that citicoline therapy enhances motor and attentional abilities and decreases impulsivity (performance on the Finger Tap Test and Ruff 2&7 Speed task after supplementation Improved.
How Does strocol Work?
• Reduces ischemic injury in the CNS by preserving membrane phospholipids, chiefly phosphatidylcholine. • Promotes rapid repair of injured cell surface and mitochondrial membranes and maintenance of cell integrity and bioenergetics capacity. • Downregulates phospholipases to avoid the production of free fatty acids and avert apoptotic and necrotic death. • In brain trauma patients, facilitates memory rehabilitation by restoring blood flow to the lesion site. • In Alzheimer's disease, improves cognitive function by serving as an acetylcholine precursor. • In Parkinson's disease, stimulates the release of dopamine neurotransmitters in the brain and can be beneficial for treatment improvement. • Repairs damage to optic nerve and improves visual acuity. • Improves attention in adolescents by increasing dopamine synthesis.
Why STROCOL?
• Strocol is a well-tolerated supplement with great bioavailability, low toxicity and few side effects. • Provides both neuroprotection and neurorepair. • Increases the probability of recovery after moderate to severe stroke. • Improves recovery in patients with traumatic brain injury? • Can be used by patients with poststroke vascular cognitive impairment. • Improves memory and behavioral outcomes in elderly? • Can be used by patients with cognitive and treatment disorders such as Alzheimer's and Parkinson's disease. • Has beneficial effects as an adjuvant therapy in patients with Parkinson's disease." • Beneficial for patients with amblvopia and glaucoma. • Can be used by adolescents with disorders involving poor attention such as ADHD.16
References
  1. Clinical Interventions in Aging 2006;  3,247-351
  2. Brain Sci. 2013.
  3. Reviews in Neurological diseases 2008; Vol. 5, No. 4.
  4. Cerebrovasc Dis 2013;  35: 146-154.
  5. Neurology 1997; 49,671.
  6. Journal of Stroke and Cerebrovascular Diseases 2014; 23, 1764-1769.
  7. Alternative Medicine Review 2004; Volume 9.
  8. stroke
  9. Arch Neurol 1996, vol 53.
  10. The Journal of Nutrition 2021;  2153-2160.
  11. Journal of Clinical Psychopharmacology 2007; 27, no. 5.
  12. Journal of Neurochemistry
  13. European Journal of Neurology 2008, 15: 465-474.
  14. Journal of attention disorders. 2019 January;  23 (2): 121-34.
  15. Clinical therapeutics. 2021 Jan 1 ;  43 (1): e19-31.
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